Bos taurus Gene: RGS20
Summary
InnateDB Gene IDBG-644406.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS20
Gene Name Regulator of G-protein signaling 20
Synonyms RSG20
Species Bos taurus
Ensembl Gene ENSBTAG00000003454
Encoded Proteins
Regulator of G-protein signaling 20
Regulator of G-protein signaling 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147509:
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:23561303-23613020
Strand Forward strand
Band
Transcripts
ENSBTAT00000004487 ENSBTAP00000004487
ENSBTAT00000052352 ENSBTAP00000049922
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0009968 negative regulation of signal transduction
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Signaling by GPCR pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (z) signalling events pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
G alpha (z) signalling events pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
G alpha (z) signalling events pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
KEGG
INOH
GPCR signaling pathway
GPCR signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.47430
RefSeq NM_001076327 XM_005215423 XM_005215424
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas