Version 5.4
Bos taurus Gene: LOC100336584
Summary
InnateDB Gene IDBG-644455.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LOC100336584
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000046547
Encoded Proteins
IDBP-697096
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176194:
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:43217455-43224463
Strand Forward strand
Band
Transcripts
ENSBTAT00000063184 ENSBTAP00000055392
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001659 temperature homeostasis
GO:0006629 lipid metabolic process
GO:0006915 apoptotic process
GO:0008219 cell death
GO:0010890 positive regulation of sequestering of triglyceride
GO:0019915 lipid storage
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0035634 response to stilbenoid
GO:0042981 regulation of apoptotic process
GO:0050995 negative regulation of lipid catabolic process
GO:1900118 negative regulation of execution phase of apoptosis
GO:1902510 regulation of apoptotic DNA fragmentation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005811 lipid particle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000176194
View Gene Order
ENSMUSG00000024526
View Gene Order
Cross-References
SwissProt
TrEMBL G3N0M6
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02056839
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca