Version 5.4
Bos taurus Gene: STMN2
Summary
InnateDB Gene IDBG-644829.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STMN2
Gene Name stathmin-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020099
Encoded Proteins
IDBP-697492
stathmin-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104435:
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down\'s syndrome and Alzheimer\'s disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:44969002-45027081
Strand Forward strand
Band
Transcripts
ENSBTAT00000026776 ENSBTAP00000026776
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0007026 negative regulation of microtubule depolymerization
GO:0010976 positive regulation of neuron projection development
GO:0010977 negative regulation of neuron projection development
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0031115 negative regulation of microtubule polymerization
GO:0031117 positive regulation of microtubule depolymerization
GO:1990090 cellular response to nerve growth factor stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0030027 lamellipodium
GO:0030426 growth cone
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104435
View Gene Order
ENSMUSG00000027500
View Gene Order
Cross-References
SwissProt
TrEMBL Q3MHJ8
UniProt Splice Variant
Entrez Gene 534991
UniGene Bt.3704
RefSeq NM_001034622
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105211 DAAA02038984 DAAA02038985 DAAA02038986
GenPept AAI05212
RNA Seq Atlas 534991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca