Version 5.4
| Bos taurus Gene: GRP | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-644899.3 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | GRP | ||||
| Gene Name | Gastrin-releasing peptide Neuromedin-C | ||||
| Synonyms | |||||
| Species | Bos taurus | ||||
| Ensembl Gene | ENSBTAG00000004796 | ||||
| Encoded Proteins |
Gastrin-releasing peptideNeuromedin-C
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134443:
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 24:58710084-58722719 | ||||
| Strand | Forward strand | ||||
| Band | |||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||
| NETPATH | |||||
| REACTOME |
Peptide hormone metabolism pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Incretin synthesis, secretion, and inactivation pathway
Peptide ligand-binding receptors pathway
Signaling by GPCR pathway
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
Signal Transduction pathway
Metabolism of proteins pathway
G alpha (q) signalling events pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
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| KEGG | |||||
| INOH | |||||
| PID NCI | |||||
| Pathway Predictions based on Human Orthology Data | |||||
| NETPATH | |||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Incretin synthesis, secretion, and inactivation pathway
Metabolism of proteins pathway
GPCR ligand binding pathway
Peptide hormone metabolism pathway
GPCR downstream signaling pathway
Incretin synthesis, secretion, and inactivation pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
Metabolism of proteins pathway
Peptide hormone metabolism pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
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| KEGG | |||||
| INOH |
GPCR signaling pathway
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| PID NCI | |||||
| Cross-References | |||||
| SwissProt | Q863C3 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 615323 | ||||
| UniGene | |||||
| RefSeq | NM_001101239 XM_005224282 XM_005224283 | ||||
| HUGO | |||||
| OMIM | |||||
| CCDS | |||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AY255852 BC149933 | ||||
| GenPept | AAI49934 AAP13050 | ||||
| RNA Seq Atlas | 615323 | ||||