InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: UQCRB

Summary

InnateDB Gene

IDBG-645215.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UQCRB

Gene Name

Cytochrome b-c1 complex subunit 7

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000001521

Encoded Proteins

IDBP-697904

Cytochrome b-c1 complex subunit 7

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156467:
This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:70329414-70334124

Strand

Forward strand

Band

Transcripts

ENSBTAT00000001993

ENSBTAP00000001993

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005750	mitochondrial respiratory chain complex III
GO:0016020	membrane
GO:0070469	respiratory chain