Version 5.4
Bos taurus Gene: LMAN2
Summary
InnateDB Gene IDBG-645241.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMAN2
Gene Name vesicular integral-membrane protein VIP36 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008034
Encoded Proteins
IDBP-697933
vesicular integral-membrane protein VIP36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169223:
This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:40185729-40206355
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010569 ENSBTAP00000010569
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005537 mannose binding
GO:0030246 carbohydrate binding
GO:0031072 heat shock protein binding
Biological Process
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0050766 positive regulation of phagocytosis
Cellular Component
GO:0005615 extracellular space
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000169223
View Gene Order
ENSMUSG00000021484
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QP36
UniProt Splice Variant
Entrez Gene 790870
UniGene Bt.76431
RefSeq NM_001101309
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149134 DAAA02020052
GenPept AAI49135
RNA Seq Atlas 790870

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca