Version 5.4
| Bos taurus Gene: IL17RD | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-645321.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | IL17RD | ||||||
| Gene Name | interleukin-17 receptor D precursor | ||||||
| Synonyms | |||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000010999 | ||||||
| Encoded Proteins |
interleukin 17 receptor D
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| InnateDB Annotation from Orthologs | |||||||
| Summary |
[Mus musculus] Intracellular Sef/IL-17R (SEFIR) domain of Il17rd targets TIR adaptor proteins Myd88, Tirap, Ticam1, Ticam2 and Traf6 to inhibit TLR downstream signalling.
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| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144730:
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin (PMID: 19079364). The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling (PMID: 21663947, 18096367). [provided by RefSeq, Nov 2011] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 22:44485036-44547391 | ||||||
| Strand | Forward strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
Disease pathway
Signaling by FGFR in disease pathway
Signal Transduction pathway
Signaling by FGFR pathway
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| KEGG | |||||||
| INOH |
FGF8 signaling (Mouse) pathway
FGF signaling pathway pathway
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| PID NCI |
FGF signaling pathway
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| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | E1BP15 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 782214 | ||||||
| UniGene | Bt.46499 | ||||||
| RefSeq | NM_001205427 XM_005222949 | ||||||
| HUGO | HGNC:17616 | ||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | DAAA02054315 DAAA02054316 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 782214 | ||||||