Version 5.4
Bos taurus Gene: BT.33253
Summary
InnateDB Gene IDBG-645868.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.33253
Gene Name myotilin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007782
Encoded Proteins
IDBP-698623
myotilin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120729:
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:50941047-50958425
Strand Forward strand
Band
Transcripts
ENSBTAT00000010231 ENSBTAP00000010231
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000120729
View Gene Order
ENSMUSG00000024471
View Gene Order
Cross-References
SwissProt
TrEMBL F1MPU4
UniProt Splice Variant
Entrez Gene 507884
UniGene Bt.33253
RefSeq NM_001075335 XM_005209363 XM_005209364 XM_005209365 XM_005209366
HUGO HGNC:12399
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020388
GenPept
RNA Seq Atlas 507884

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca