Bos taurus Gene: PRMT5
Summary
InnateDB Gene IDBG-645872.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRMT5
Gene Name protein arginine N-methyltransferase 5
Synonyms SKB1
Species Bos taurus
Ensembl Gene ENSBTAG00000010890
Encoded Proteins
protein arginine N-methyltransferase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100462:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:21752766-21760473
Strand Forward strand
Band
Transcripts
ENSBTAT00000014463 ENSBTAP00000014463
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 96 interaction(s) predicted by orthology.
Predicted by orthology
Total 96 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008469 histone-arginine N-methyltransferase activity
GO:0016740 transferase activity
GO:0035243 protein-arginine omega-N symmetric methyltransferase activity
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000387 spliceosomal snRNP assembly
GO:0006355 regulation of transcription, DNA-templated
GO:0006479 protein methylation
GO:0018216 peptidyl-arginine methylation
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0032259 methylation
GO:0034969 histone arginine methylation
GO:0035246 peptidyl-arginine N-methylation
GO:0042118 endothelial cell activation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0034709 methylosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
snRNP Assembly pathway
Metabolism of non-coding RNA pathway
Chromatin organization pathway
RMTs methylate histone arginines pathway
Chromatin modifying enzymes pathway
Gene Expression pathway
Chromatin organization pathway
Metabolism of non-coding RNA pathway
Chromatin modifying enzymes pathway
snRNP Assembly pathway
Gene Expression pathway
RMTs methylate histone arginines pathway
KEGG
RNA transport pathway
RNA transport pathway
INOH
PID NCI
Signaling events mediated by HDAC Class I
p53 pathway
E2F transcription factor network
Cross-References
SwissProt
TrEMBL F1N443
UniProt Splice Variant
Entrez Gene 515594
UniGene Bt.16112
RefSeq NM_001105374 XM_005211326 XM_005211327 XM_005211328
HUGO HGNC:10894
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02028045
GenPept
RNA Seq Atlas 515594