Version 5.4
Homo sapiens Gene: SLCO2B1
Summary
InnateDB Gene IDBG-64595.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLCO2B1
Gene Name solute carrier organic anion transporter family, member 2B1
Synonyms OATP-B; OATP2B1; OATPB; SLC21A9
Species Homo sapiens
Ensembl Gene ENSG00000137491
Encoded Proteins
IDBP-64597
solute carrier organic anion transporter family, member 2B1
IDBP-381101
solute carrier organic anion transporter family, member 2B1
IDBP-381103
solute carrier organic anion transporter family, member 2B1
IDBP-587468
solute carrier organic anion transporter family, member 2B1
IDBP-601484
solute carrier organic anion transporter family, member 2B1
IDBP-583874
solute carrier organic anion transporter family, member 2B1
IDBP-583422
solute carrier organic anion transporter family, member 2B1
IDBP-591549
solute carrier organic anion transporter family, member 2B1
IDBP-587561
solute carrier organic anion transporter family, member 2B1
IDBP-586010
solute carrier organic anion transporter family, member 2B1
IDBP-587116
solute carrier organic anion transporter family, member 2B1
IDBP-603768
solute carrier organic anion transporter family, member 2B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:75100563-75206549
Strand Forward strand
Band q13.4
Transcripts
ENST00000289575 ENSP00000289575
ENST00000341411
ENST00000428359 ENSP00000388912
ENST00000454962 ENSP00000389653
ENST00000526660
ENST00000531713 ENSP00000432889
ENST00000532236 ENSP00000434112
ENST00000531756
ENST00000531457
ENST00000525650 ENSP00000436324
ENST00000530556 ENSP00000435384
ENST00000534004 ENSP00000431192
ENST00000527180 ENSP00000436513
ENST00000525845 ENSP00000431324
ENST00000534186 ENSP00000433872
ENST00000526839 ENSP00000434742
ENST00000530012
ENST00000528108
ENST00000530015
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008514 organic anion transmembrane transporter activity
GO:0015125 bile acid transmembrane transporter activity
GO:0015347 sodium-independent organic anion transmembrane transporter activity
Biological Process
GO:0001889 liver development
GO:0006810 transport
GO:0015721 bile acid and bile salt transport
GO:0043252 sodium-independent organic anion transport
GO:0055085 transmembrane transport
GO:0071718 sodium-independent icosanoid transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030737
View Gene Order
ENSBTAG00000015596
Not yet available
Pathways
NETPATH
REACTOME
REACT_23988
Transport of organic anions pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.642301 Hs.712697 Hs.7884
RefSeq NM_001145211 NM_001145212 NM_007256 XM_006718427
HUGO
OMIM
CCDS CCDS44683 CCDS53679 CCDS8235
HPRD 07061
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca