Bos taurus Gene: DAAM1 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||
InnateDB Gene | IDBG-646738.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | DAAM1 | ||||||||||||
Gene Name | disheveled-associated activator of morphogenesis 1 | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000005984 | ||||||||||||
Encoded Proteins |
disheveled-associated activator of morphogenesis 1
|
||||||||||||
Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100592:
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012] |
||||||||||||
Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 10:71730213-71916529 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
|
||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
|
||||||||||||
Gene Ontology | |||||||||||||
Molecular Function |
|
||||||||||||
Biological Process |
|
||||||||||||
Cellular Component |
|
||||||||||||
Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH |
Wnt pathway
|
||||||||||||
REACTOME |
PCP/CE pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Signal Transduction pathway
Signaling by Wnt pathway
beta-catenin independent WNT signaling pathway
PCP/CE pathway pathway
Signal Transduction pathway
|
||||||||||||
KEGG |
Wnt signaling pathway pathway
Wnt signaling pathway pathway
|
||||||||||||
INOH | |||||||||||||
PID NCI |
Noncanonical Wnt signaling pathway
|
||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | A2VDK3 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 538749 | ||||||||||||
UniGene | Bt.8208 | ||||||||||||
RefSeq | NM_001081588 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC133280 DAAA02029283 DAAA02029284 DAAA02029285 DAAA02029286 DAAA02029287 DAAA02029288 | ||||||||||||
GenPept | AAI33281 | ||||||||||||
RNA Seq Atlas | 513742 538749 | ||||||||||||