Version 5.4
Bos taurus Gene: RHOJ
Summary
InnateDB Gene IDBG-646762.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RHOJ
Gene Name rho-related GTP-binding protein RhoJ
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017200
Encoded Proteins
IDBP-699593
rho-related GTP-binding protein RhoJ
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126785:
This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:75783882-75877395
Strand Forward strand
Band
Transcripts
ENSBTAT00000022858 ENSBTAP00000022858
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007266 Rho protein signal transduction
GO:0008360 regulation of cell shape
GO:0015031 protein transport
GO:0030036 actin cytoskeleton organization
GO:0061299 retina vasculature morphogenesis in camera-type eye
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000126785
View Gene Order
ENSMUSG00000046768
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A4FV20
UniProt Splice Variant
Entrez Gene 540619
UniGene Bt.28269
RefSeq NM_001083498
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123637 DAAA02029381 DAAA02029382
GenPept AAI23638
RNA Seq Atlas 540619

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca