Bos taurus Gene: KCNJ6
Summary
InnateDB Gene IDBG-647363.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ6
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000037616
Encoded Proteins
potassium inwardly-rectifying channel, subfamily J, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157542:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151610045-151610971
Strand Reverse strand
Band
Transcripts
ENSBTAT00000052335 ENSBTAP00000049141
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005244 voltage-gated ion channel activity
GO:0005515 protein binding
GO:0015467 G-protein activated inward rectifier potassium channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
GABA B receptor activation pathway
Activation of G protein gated Potassium channels pathway
Neuronal System pathway
GABA receptor activation pathway
G protein gated Potassium channels pathway
Activation of GABAB receptors pathway
Inwardly rectifying K+ channels pathway
Potassium Channels pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Inwardly rectifying K+ channels pathway
G protein gated Potassium channels pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Activation of GABAB receptors pathway
Potassium Channels pathway
GABA B receptor activation pathway
GABA receptor activation pathway
Neuronal System pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
Transmission across Chemical Synapses pathway
Activation of G protein gated Potassium channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MUD1
UniProt Splice Variant
Entrez Gene 520743
UniGene
RefSeq XM_002685169 XM_005196020 XM_598993
HUGO HGNC:6267
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003591
GenPept
RNA Seq Atlas 520743