Version 5.4
Bos taurus Gene: ATOH1
Summary
InnateDB Gene IDBG-648579.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATOH1
Gene Name protein atonal homolog 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002895
Encoded Proteins
IDBP-701313
protein atonal homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172238:
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:32136547-32138712
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003762 ENSBTAP00000003762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001764 neuron migration
GO:0007411 axon guidance
GO:0007420 brain development
GO:0021987 cerebral cortex development
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0042472 inner ear morphogenesis
GO:0042491 auditory receptor cell differentiation
GO:0042667 auditory receptor cell fate specification
GO:0042668 auditory receptor cell fate determination
GO:0043066 negative regulation of apoptotic process
GO:0045609 positive regulation of auditory receptor cell differentiation
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048839 inner ear development
GO:2000982 positive regulation of inner ear receptor cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000172238
View Gene Order
ENSMUSG00000073043
View Gene Order
Cross-References
SwissProt
TrEMBL A4IFC1
UniProt Splice Variant
Entrez Gene 539158
UniGene Bt.29000
RefSeq NM_001098099
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134506 DAAA02016933
GenPept AAI34507
RNA Seq Atlas 539158

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca