Homo sapiens Gene: PITPNC1
Summary
InnateDB Gene IDBG-65469.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PITPNC1
Gene Name phosphatidylinositol transfer protein, cytoplasmic 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154217
Encoded Proteins
phosphatidylinositol transfer protein, cytoplasmic 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the phosphatidylinositol transfer protein family. The encoded cytoplasmic protein plays a role in multiple processes including cell signaling and lipid metabolism by facilitating the transfer of phosphatidylinositol between membrane compartments. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:67377281-67697261
Strand Forward strand
Band q24.2
Transcripts
ENST00000299954 ENSP00000299954
ENST00000578527
ENST00000581322 ENSP00000464006
ENST00000584471 ENSP00000464584
ENST00000581923
ENST00000580974 ENSP00000463626
ENST00000584554 ENSP00000464364
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0008526 phosphatidylinositol transporter activity
Biological Process
GO:0006810 transport
GO:0007165 signal transduction
GO:0015914 phospholipid transport
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt
TrEMBL J3QS95
UniProt Splice Variant
Entrez Gene 26207
UniGene Hs.591185 Hs.631157
RefSeq NM_181671 NM_012417
HUGO HGNC:21045
OMIM 605134
CCDS CCDS58587 CCDS58588
HPRD 05504
IMGT
EMBL AC079331 AC110921
GenPept
RNA Seq Atlas 26207