Homo sapiens Gene: CDC42EP1
Summary
InnateDB Gene IDBG-6662.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDC42EP1
Gene Name CDC42 effector protein (Rho GTPase binding) 1
Synonyms BORG5; CEP1; MSE55;
Species Homo sapiens
Ensembl Gene ENSG00000128283
Encoded Proteins
CDC42 effector protein (Rho GTPase binding) 1
CDC42 effector protein (Rho GTPase binding) 1
CDC42 effector protein (Rho GTPase binding) 1
CDC42 effector protein (Rho GTPase binding) 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:37560447-37569405
Strand Forward strand
Band q13.1
Transcripts
ENST00000249014 ENSP00000249014
ENST00000430687 ENSP00000411682
ENST00000415670 ENSP00000405006
ENST00000434728 ENSP00000403710
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007266 Rho protein signal transduction
GO:0008360 regulation of cell shape
GO:0031274 positive regulation of pseudopodium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL B0QYC6
UniProt Splice Variant
Entrez Gene 11135
UniGene Hs.225356 Hs.594639
RefSeq NM_152243 XM_006724107 XM_006724108 XM_006724109
HUGO HGNC:17014
OMIM 606084
CCDS CCDS13949
HPRD 07303
IMGT
EMBL AL022315
GenPept
RNA Seq Atlas 11135