Mus musculus Gene: Pou3f2
Summary
InnateDB Gene IDBG-707989.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pou3f2
Gene Name POU domain, class 3, transcription factor 2
Synonyms 9430075J19Rik; A230098E07Rik; Brn-2; Brn2; oct-7; OTF-7; Otf7;
Species Mus musculus
Ensembl Gene ENSMUSG00000095139
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184486:
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:22482780-22488366
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000178174 ENSMUSP00000136147
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001105 RNA polymerase II transcription coactivator activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0008284 positive regulation of cell proliferation
GO:0008544 epidermis development
GO:0014002 astrocyte development
GO:0014044 Schwann cell development
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021869 forebrain ventricular zone progenitor cell division
GO:0021979 hypothalamus cell differentiation
GO:0021985 neurohypophysis development
GO:0022011 myelination in peripheral nervous system
GO:0030182 neuron differentiation
GO:0040018 positive regulation of multicellular organism growth
GO:0045595 regulation of cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050770 regulation of axonogenesis
GO:0071310 cellular response to organic substance
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt P31360
TrEMBL
UniProt Splice Variant
Entrez Gene 18992
UniGene Mm.389520 Mm.405968 Mm.411421 Mm.486031 Mm.487599 Mm.487875 Mm.487894
RefSeq NM_008899
OMIM
CCDS CCDS18005
HPRD
IMGT
MGI ID MGI:101895
MGI Symbol Pou3f2
EMBL AL772230 M88300
GenPept AAA39961 CAM22634
RNA Seq Atlas 18992