Version 5.4
Homo sapiens Gene: MARCH7
Summary
InnateDB Gene IDBG-73259.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARCH7
Gene Name membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136536
Encoded Proteins
IDBP-73261
membrane-associated ring finger (C3HC4) 7
IDBP-293913
membrane-associated ring finger (C3HC4) 7
IDBP-293916
membrane-associated ring finger (C3HC4) 7
IDBP-386854
membrane-associated ring finger (C3HC4) 7
IDBP-386856
membrane-associated ring finger (C3HC4) 7
IDBP-589663
membrane-associated ring finger (C3HC4) 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:159712457-159771027
Strand Forward strand
Band q24.2
Transcripts
ENST00000259050 ENSP00000259050
ENST00000409175 ENSP00000386830
ENST00000409591 ENSP00000387238
ENST00000421037 ENSP00000392862
ENST00000420397 ENSP00000391493
ENST00000473749
ENST00000461582
ENST00000478396
ENST00000539065 ENSP00000442992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026977
View Gene Order
ENSBTAG00000008755
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001282805 NM_001282806 NM_001282807 NM_022826 XM_005246773
HUGO
OMIM
CCDS CCDS2210 CCDS63038 CCDS63039
HPRD 09817
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca