Homo sapiens Gene: DSN1
Summary
InnateDB Gene IDBG-73404.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSN1
Gene Name DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000149636
Encoded Proteins
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:36751791-36773818
Strand Reverse strand
Band q11.23
Transcripts
ENST00000373750 ENSP00000362855
ENST00000373740 ENSP00000362845
ENST00000373734 ENSP00000362839
ENST00000448110 ENSP00000404463
ENST00000426836 ENSP00000389810
ENST00000447406 ENSP00000399654
ENST00000438549 ENSP00000395760
ENST00000480153
ENST00000473615
ENST00000492703
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0051301 cell division
Cellular Component
GO:0000444 MIS12/MIND type complex
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9H410
TrEMBL Q5JW53 Q5JW57
UniProt Splice Variant
Entrez Gene 79980
UniGene Hs.632268
RefSeq NM_001145315 XM_005260558 NM_001145316 NM_001145317 NM_001145318 NM_024918 XM_005260559 XM_006723876
HUGO HGNC:16165
OMIM 609175
CCDS CCDS13286 CCDS46596 CCDS46597
HPRD 16455
IMGT
EMBL AK023408 AK093031 AK301671 AK301840 AL132768 BC058899 CH471077
GenPept AAH58899 BAB14564 BAC04024 BAG63144 BAG63283 CAC10099 CAI21468 EAW76101 EAW76102 EAW76104 EAW76106
RNA Seq Atlas 79980