Version 5.4
Homo sapiens Gene: CDCA7
Summary
InnateDB Gene IDBG-75261.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDCA7
Gene Name cell division cycle associated 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144354
Encoded Proteins
IDBP-75263
cell division cycle associated 7
IDBP-75265
cell division cycle associated 7
IDBP-293599
cell division cycle associated 7
IDBP-293596
cell division cycle associated 7
IDBP-387633
cell division cycle associated 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:173354820-173368997
Strand Forward strand
Band q31.1
Transcripts
ENST00000306721 ENSP00000306968
ENST00000347703 ENSP00000272789
ENST00000410101 ENSP00000386656
ENST00000410019 ENSP00000386833
ENST00000435616 ENSP00000390470
ENST00000496441
ENST00000467411
ENST00000468359
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055612
View Gene Order
ENSBTAG00000003458
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
myc_activpathway
Validated targets of C-MYC transcriptional activation
Cross-References
SwissProt Q9BWT1
TrEMBL B4DM13
UniProt Splice Variant
Entrez Gene 83879
UniGene Hs.470654 Hs.630838
RefSeq NM_145810 NM_031942
HUGO HGNC:14628
OMIM 609937
CCDS CCDS2253 CCDS2252
HPRD 09874
IMGT
EMBL AC092573 AK027628 AK027642 AK075134 AK223524 AK297097 AK297245 AK300949 AL833728 AL834186 AY029179 BC015124 BC027966 BG354580
GenPept AAH15124 AAH27966 AAK31591 AAX82003 BAB55245 BAB55258 BAC11425 BAD97244 BAG59610 BAG59725 BAG62578 CAH56253 CAH56357
RNA Seq Atlas 83879

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca