Version 5.4
Homo sapiens Gene: CKS2
Summary
InnateDB Gene IDBG-75306.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CKS2
Gene Name CDC28 protein kinase regulatory subunit 2
Synonyms CKSHS2
Species Homo sapiens
Ensembl Gene ENSG00000123975
Encoded Proteins
IDBP-75308
CDC28 protein kinase regulatory subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:89311198-89316703
Strand Forward strand
Band q22.2
Transcripts
ENST00000314355 ENSP00000364976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 26 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0007049 cell cycle
GO:0007051 spindle organization
GO:0007127 meiosis I
GO:0008283 cell proliferation
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000062248
View Gene Order
ENSBTAG00000001938
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05222
Small cell lung cancer pathway
hsa05200
Pathways in cancer pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001827
HUGO
OMIM
CCDS CCDS6682
HPRD 00300
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca