Homo sapiens Gene: TUBB
Summary
InnateDB Gene IDBG-76778.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBB
Gene Name tubulin, beta class I
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196230
Encoded Proteins
tubulin, beta class I
tubulin, beta class I
tubulin, beta class I
tubulin, beta class I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30720201-30725426
Strand Forward strand
Band p21.33
Transcripts
ENST00000327892 ENSP00000339001
ENST00000330914 ENSP00000365578
ENST00000396389 ENSP00000379672
ENST00000396384 ENSP00000379668
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 213 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 213 [view]
Protein-Protein 213 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019904 protein domain specific binding
GO:0032403 protein complex binding
GO:0032794 GTPase activating protein binding
GO:0042288 MHC class I protein binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0006184 GTP catabolic process
GO:0006928 cellular component movement
GO:0007017 microtubule-based process
GO:0009987 cellular process
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0042267 natural killer cell mediated cytotoxicity
GO:0051225 spindle assembly
GO:0051258 protein polymerization
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005641 nuclear envelope lumen
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043234 protein complex
GO:0044297 cell body
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
TCR pathway
REACTOME
Loss of Nlp from mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Mitotic G2-G2/M phases pathway
KEGG
Phagosome pathway
Gap junction pathway
Pathogenic Escherichia coli infection pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P07437
TrEMBL A4UCU2 Q5JP53 Q5ST81 Q5SU16 Q6P602 Q96B85 Q9BUU9
UniProt Splice Variant
Entrez Gene 203068
UniGene Hs.636480
RefSeq NM_001293215 NM_178014
HUGO HGNC:20778
OMIM 191130
CCDS CCDS4687
HPRD
IMGT
EMBL AB062393 AB088100 AB103606 AB202098 AF070561 AF070593 AF070600 AF141349 AL662797 BA000025 BC001896 BC001938 BC002347 BC005838 BC007605 BC013374 BC015889 BC019924 BC020946 BC021909 BC062532 BC070326 BC103746 CH471081 EF036509 J00314
GenPept AAB59507 AAC28642 AAC28650 AAC28654 AAD33873 AAH01896 AAH01938 AAH02347 AAH05838 AAH07605 AAH13374 AAH15889 AAH19924 AAH20946 AAH21909 AAH62532 AAH70326 AAI03747 ABO65095 BAB63321 BAB93480 BAC54932 BAE78618 BAF31267 EAX03322 EAX03323
RNA Seq Atlas 203068