Version 5.4
Homo sapiens Gene: AIMP2
Summary
InnateDB Gene IDBG-8010.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AIMP2
Gene Name aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Synonyms JTV-1; JTV1; P38
Species Homo sapiens
Ensembl Gene ENSG00000106305
Encoded Proteins
IDBP-8012
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
IDBP-228154
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
IDBP-239974
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
IDBP-363507
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:6009245-6023834
Strand Forward strand
Band p22.1
Transcripts
ENST00000223029 ENSP00000223029
ENST00000400479 ENSP00000383327
ENST00000395236 ENSP00000378658
ENST00000415999 ENSP00000392519
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 101 experimentally validated interaction(s) in this database.
Experimentally validated
Total 101 [view]
Protein-Protein 98 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006915 apoptotic process
GO:0008285 negative regulation of cell proliferation
GO:0010467 gene expression
GO:0031398 positive regulation of protein ubiquitination
GO:0060510 Type II pneumocyte differentiation
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029610
View Gene Order
ENSBTAG00000007367
Not yet available
Pathways
NETPATH
REACTOME
REACT_15306
Cytosolic tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8W950
UniProt Splice Variant
Entrez Gene 7965
UniGene
RefSeq NM_006303 XM_005249850 XM_006715772
HUGO HGNC:20609
OMIM 600859
CCDS CCDS5344
HPRD 02915
IMGT
EMBL AC005995
GenPept
RNA Seq Atlas 7965

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca