|Homo sapiens Gene: RING1|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||ring finger protein 1|
ring finger protein 1
|Useful resources||Stemformatics EHFPI ImmGen|
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 6:33208495-33212722|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 99 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Cellular responses to stress pathway
Cellular Senescence pathway
Oxidative Stress Induced Senescence pathway
|UniProt Splice Variant|
|RNA Seq Atlas|