Homo sapiens Gene: RPA3
InnateDB Gene IDBG-8521.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPA3
Gene Name replication protein A3, 14kDa
Synonyms REPA3
Species Homo sapiens
Ensembl Gene ENSG00000106399
Encoded Proteins
replication protein A3, 14kDa
replication protein A3, 14kDa
replication protein A3, 14kDa
replication protein A3, 14kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:7636518-7718607
Strand Reverse strand
Band p21.3
ENST00000223129 ENSP00000223129
ENST00000396682 ENSP00000379914
ENST00000406109 ENSP00000384652
ENST00000401447 ENSP00000385383
Number of Interactions This gene and/or its encoded proteins are associated with 388 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 388 [view]
Protein-Protein 384 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 2 [view]
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0000718 nucleotide-excision repair, DNA damage removal
GO:0000722 telomere maintenance via recombination
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000730 DNA recombinase assembly
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006284 base-excision repair
GO:0006289 nucleotide-excision repair
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006298 mismatch repair
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0007346 regulation of mitotic cell cycle
GO:0032201 telomere maintenance via semi-conservative replication
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005662 DNA replication factor A complex
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Activation of ATR in response to replication stress pathway
Removal of the Flap Intermediate from the C-strand pathway
Processive synthesis on the C-strand of the telomere pathway
Telomere C-strand (Lagging Strand) Synthesis pathway
Removal of the Flap Intermediate pathway
Processive synthesis on the lagging strand pathway
Activation of the pre-replicative complex pathway
Repair synthesis for gap-filling by DNA polymerase in TC-NER pathway
Gap-filling DNA repair synthesis and ligation in TC-NER pathway
Transcription-coupled NER (TC-NER) pathway
Dual incision reaction in GG-NER pathway
Formation of incision complex in GG-NER pathway
Repair synthesis of patch ~27-30 bases long by DNA polymerase pathway
Gap-filling DNA repair synthesis and ligation in GG-NER pathway
Processing of DNA double-strand break ends pathway
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
Homologous DNA pairing and strand exchange pathway
Meiotic recombination pathway
DNA Replication pathway
Cellular responses to stress pathway
Synthesis of DNA pathway
Regulation of HSF1-mediated heat shock response pathway
Homologous Recombination Repair pathway
Mitotic G1-G1/S phases pathway
S Phase pathway
Chromosome Maintenance pathway
G2/M Checkpoints pathway
DNA Replication Pre-Initiation pathway
Global Genomic NER (GG-NER) pathway
Telomere Maintenance pathway
G1/S Transition pathway
Double-Strand Break Repair pathway
Cell Cycle pathway
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) pathway
Cellular response to heat stress pathway
M/G1 Transition pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
Cell Cycle, Mitotic pathway
DNA strand elongation pathway
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) pathway
Mismatch Repair pathway
Meiosis pathway
HSF1 activation pathway
Extension of Telomeres pathway
Lagging Strand Synthesis pathway
Nucleotide Excision Repair pathway
DNA Repair pathway
Cell Cycle Checkpoints pathway
DNA replication pathway
Nucleotide excision repair pathway
Homologous recombination pathway
Mismatch repair pathway
UniProt Splice Variant
Entrez Gene
UniGene Hs.487540 Hs.738841
RefSeq NM_002947
HPRD 01567
RNA Seq Atlas