Homo sapiens Gene: TREML4 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-86619.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | TREML4 | ||||||
Gene Name | triggering receptor expressed on myeloid cells-like 4 | ||||||
Synonyms | |||||||
Species | Homo sapiens | ||||||
Ensembl Gene | ENSG00000188056 | ||||||
Encoded Proteins |
triggering receptor expressed on myeloid cells-like 4
triggering receptor expressed on myeloid cells-like 4
triggering receptor expressed on myeloid cells-like 4
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
InnateDB Annotation from Orthologs | |||||||
Summary |
[Mus musculus] Treml4 is an essential positive regulator of Tlr7 signalling. Treml4(-/-) macrophages are hyporesponsive to Tlr7 agonists and fail to produce type I interferons due to impaired phosphorylation of Stat1 by Mapk14 and decreased recruitment of Myd88 to Tlr7.
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Entrez Gene | |||||||
Summary | Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs. | ||||||
Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 6:41228324-41238882 | ||||||
Strand | Forward strand | ||||||
Band | p21.1 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 285852 | ||||||
UniGene | Hs.434181 | ||||||
RefSeq | NM_198153 XM_005249025 | ||||||
HUGO | HGNC:30807 | ||||||
OMIM | 614664 | ||||||
CCDS | CCDS34446 | ||||||
HPRD | 15548 | ||||||
IMGT | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | 285852 | ||||||