Homo sapiens Gene: PGK2
Summary
InnateDB Gene IDBG-90293.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGK2
Gene Name phosphoglycerate kinase 2
Synonyms dJ417L20.2; HEL-S-272; PGKB; PGKPS;
Species Homo sapiens
Ensembl Gene ENSG00000170950
Encoded Proteins
phosphoglycerate kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:49785934-49787187
Strand Reverse strand
Band p12.3
Transcripts
ENST00000304801 ENSP00000305995
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004618 phosphoglycerate kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006096 glycolytic process
GO:0016310 phosphorylation
GO:0030317 sperm motility
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005929 cilium
GO:0035686 sperm fibrous sheath
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
Glycolysis / Gluconeogenesis pathway
INOH
Glycolysis Gluconeogenesis pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt P07205
TrEMBL
UniProt Splice Variant
Entrez Gene 5232
UniGene Hs.367727
RefSeq NM_138733
HUGO HGNC:8898
OMIM 172270
CCDS CCDS4930
HPRD
IMGT
EMBL AK312770 AL121974 BC038843 X05246
GenPept AAH38843 BAG35635 CAA28872 CAC19655
RNA Seq Atlas 5232