Homo sapiens Gene: ABLIM1
Summary
InnateDB Gene IDBG-90406.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABLIM1
Gene Name actin binding LIM protein 1
Synonyms ABLIM; abLIM-1; LIMAB1; LIMATIN;
Species Homo sapiens
Ensembl Gene ENSG00000099204
Encoded Proteins
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
actin binding LIM protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:114431113-114685003
Strand Reverse strand
Band q25.3
Transcripts
ENST00000369266 ENSP00000358270
ENST00000369256 ENSP00000358260
ENST00000277895 ENSP00000277895
ENST00000369253 ENSP00000358257
ENST00000369252 ENSP00000358256
ENST00000392955 ENSP00000376682
ENST00000392952 ENSP00000376679
ENST00000440467 ENSP00000414154
ENST00000428430 ENSP00000400934
ENST00000485570
ENST00000466400
ENST00000481974
ENST00000477638
ENST00000533213 ENSP00000433629
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007411 axon guidance
GO:0007601 visual perception
GO:0009887 organ morphogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Developmental Biology pathway
Axon guidance pathway
Netrin-1 signaling pathway
DCC mediated attractive signaling pathway
KEGG
Axon guidance pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt O14639
TrEMBL
UniProt Splice Variant
Entrez Gene 3983
UniGene Hs.645719
RefSeq XM_005269818 XM_006717840 XM_006717841 NM_006720 NM_001003408 NM_001003407 NM_002313 XM_005269828 XM_006717848 XM_005269822 XM_006717844 XM_005269820 XM_005269819 XM_006717843
HUGO HGNC:78
OMIM 602330
CCDS CCDS31289 CCDS7590
HPRD 03819
IMGT
EMBL AF005654 AK098277 AL133384 AL354873 AL590109 BC002448 CR749819 D31883
GenPept AAC51676 AAH02448 BAA06681 BAG53605 CAH18679 CAI10908 CAI10910 CAI40135 CAI40136 CAI40140 CAI40141
RNA Seq Atlas 3983