Homo sapiens Gene: RCC1
Summary
InnateDB Gene IDBG-95231.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCC1
Gene Name regulator of chromosome condensation 1
Synonyms CHC1; RCC1-I; SNHG3-RCC1;
Species Homo sapiens
Ensembl Gene ENSG00000180198
Encoded Proteins
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
regulator of chromosome condensation 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:28505943-28539300
Strand Forward strand
Band p35.3
Transcripts
ENST00000373833 ENSP00000362939
ENST00000373832 ENSP00000362938
ENST00000373831 ENSP00000362937
ENST00000398958 ENSP00000381931
ENST00000427469 ENSP00000402740
ENST00000434290 ENSP00000405258
ENST00000419074 ENSP00000402260
ENST00000411533 ENSP00000413644
ENST00000430407 ENSP00000394650
ENST00000429051
ENST00000486790 ENSP00000472057
ENST00000478232
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 104 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 104 [view]
Protein-Protein 104 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005087 Ran guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0031492 nucleosomal DNA binding
GO:0042393 histone binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0007052 mitotic spindle organization
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0007088 regulation of mitosis
GO:0016032 viral process
GO:0032316 regulation of Ran GTPase activity
GO:0032853 positive regulation of Ran GTPase activity
GO:0051225 spindle assembly
Cellular Component
GO:0000790 nuclear chromatin
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Late Phase of HIV Life Cycle pathway
HIV Life Cycle pathway
Rev-mediated nuclear export of HIV RNA pathway
HIV Infection pathway
Nuclear import of Rev protein pathway
Host Interactions of HIV factors pathway
Interactions of Rev with host cellular proteins pathway
Disease pathway
KEGG
INOH
PID BIOCARTA
Role of ran in mitotic spindle regulation [Biocarta view]
Mechanism of protein import into the nucleus [Biocarta view]
Cycling of ran in nucleocytoplasmic transport [Biocarta view]
PID NCI
Validated targets of C-MYC transcriptional activation
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.469723
RefSeq NM_001048194 NM_001048195 NM_001048199 NM_001269
HUGO
OMIM
CCDS CCDS323 CCDS41295
HPRD 01559
IMGT
EMBL
GenPept
RNA Seq Atlas