Version 5.4
Homo sapiens Gene: CSGALNACT1
Summary
InnateDB Gene IDBG-9548.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSGALNACT1
Gene Name chondroitin sulfate N-acetylgalactosaminyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147408
Encoded Proteins
IDBP-9550
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-234105
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-362008
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-481460
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-482402
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-479528
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-481643
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-475715
chondroitin sulfate N-acetylgalactosaminyltransferase 1
IDBP-480291
chondroitin sulfate N-acetylgalactosaminyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:19404161-19758029
Strand Reverse strand
Band p21.3
Transcripts
ENST00000332246 ENSP00000330805
ENST00000397998 ENSP00000381084
ENST00000454498 ENSP00000411816
ENST00000522854 ENSP00000429809
ENST00000518542
ENST00000519222 ENSP00000428216
ENST00000523262 ENSP00000428089
ENST00000517494 ENSP00000429130
ENST00000520003 ENSP00000428774
ENST00000524213 ENSP00000427740
ENST00000517651
ENST00000523227
ENST00000522732
ENST00000522573
ENST00000523919
ENST00000524112
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008376 acetylgalactosaminyltransferase activity
GO:0008955 peptidoglycan glycosyltransferase activity
GO:0015020 glucuronosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0046872 metal ion binding
GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
Biological Process
GO:0001958 endochondral ossification
GO:0005975 carbohydrate metabolic process
GO:0007399 nervous system development
GO:0008037 cell recognition
GO:0008283 cell proliferation
GO:0009653 anatomical structure morphogenesis
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0019276 UDP-N-acetylgalactosamine metabolic process
GO:0030166 proteoglycan biosynthetic process
GO:0030198 extracellular matrix organization
GO:0030203 glycosaminoglycan metabolic process
GO:0030204 chondroitin sulfate metabolic process
GO:0030206 chondroitin sulfate biosynthetic process
GO:0030210 heparin biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046398 UDP-glucuronate metabolic process
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process
GO:0050651 dermatan sulfate proteoglycan biosynthetic process
GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0051216 cartilage development
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0030173 integral component of Golgi membrane
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036356
View Gene Order
ENSBTAG00000004613
Not yet available
Pathways
NETPATH
REACTOME
REACT_120989
Chondroitin sulfate biosynthesis pathway
REACT_147853
Mucopolysaccharidoses pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_267711
Defective B4GALT7 causes EDS, progeroid type pathway
REACT_267713
Defective CHST6 causes MCDC1 pathway
REACT_147719
MPS VI - Maroteaux-Lamy syndrome pathway
REACT_267645
Defective PAPSS2 causes SEMD-PA pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_147749
MPS IIID - Sanfilippo syndrome D pathway
REACT_267662
Defective SLC26A2 causes chondrodysplasias pathway
REACT_147739
MPS IX - Natowicz syndrome pathway
REACT_267674
Defective EXT1 causes exostoses 1, TRPS2 and CHDS pathway
REACT_267642
Defective CHST14 causes EDS, musculocontractural type pathway
REACT_147798
MPS IV - Morquio syndrome B pathway
REACT_267659
Defective B3GAT3 causes JDSSDHD pathway
REACT_267708
Defective CHST3 causes SEDCJD pathway
REACT_147825
MPS IV - Morquio syndrome A pathway
REACT_267654
Defective EXT2 causes exostoses 2 pathway
REACT_267707
Diseases associated with glycosaminoglycan metabolism pathway
REACT_147734
MPS II - Hunter syndrome pathway
REACT_267635
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) pathway
REACT_121315
Glycosaminoglycan metabolism pathway
REACT_267705
Diseases of glycosylation pathway
REACT_121206
Chondroitin sulfate/dermatan sulfate metabolism pathway
REACT_147759
MPS VII - Sly syndrome pathway
REACT_267682
Defective CHSY1 causes TPBS pathway
REACT_111217
Metabolism pathway
REACT_147857
MPS I - Hurler syndrome pathway
REACT_147753
MPS IIIA - Sanfilippo syndrome A pathway
REACT_147860
MPS IIIC - Sanfilippo syndrome C pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
REACT_147788
MPS IIIB - Sanfilippo syndrome B pathway
KEGG
hsa00532
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.613729 Hs.721954
RefSeq NM_001130518 NM_018371 XM_006716358 XM_006716359 XM_006716360 XM_006716361 XM_006716362 XM_006716363 XM_006716364 XM_006716365 XM_006716366
HUGO
OMIM
CCDS CCDS6010
HPRD 13114
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca