Homo sapiens Gene: INTS10
Summary
InnateDB Gene IDBG-9603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS10
Gene Name integrator complex subunit 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104613
Encoded Proteins
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
integrator complex subunit 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:19817140-19852083
Strand Forward strand
Band p21.3
Transcripts
ENST00000397977 ENSP00000381064
ENST00000518424 ENSP00000429011
ENST00000522114 ENSP00000430877
ENST00000520985
ENST00000521758
ENST00000523869 ENSP00000428107
ENST00000522081
ENST00000523846 ENSP00000430446
ENST00000522806
ENST00000523143
ENST00000521357 ENSP00000430704
ENST00000518799 ENSP00000429534
ENST00000519493
ENST00000520670 ENSP00000429117
ENST00000521008 ENSP00000428300
ENST00000523772 ENSP00000428608
ENST00000520827 ENSP00000428671
ENST00000517546
ENST00000607660
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.512627
RefSeq NM_018142 XM_005273557
HUGO
OMIM
CCDS CCDS6011
HPRD 07686
IMGT
EMBL
GenPept
RNA Seq Atlas