Version 5.4
Homo sapiens Gene: INTS10
Summary
InnateDB Gene IDBG-9603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS10
Gene Name integrator complex subunit 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104613
Encoded Proteins
IDBP-234128
integrator complex subunit 10
IDBP-475748
integrator complex subunit 10
IDBP-483756
integrator complex subunit 10
IDBP-474313
integrator complex subunit 10
IDBP-481642
integrator complex subunit 10
IDBP-479407
integrator complex subunit 10
IDBP-484302
integrator complex subunit 10
IDBP-473850
integrator complex subunit 10
IDBP-485130
integrator complex subunit 10
IDBP-475776
integrator complex subunit 10
IDBP-484863
integrator complex subunit 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:19817140-19852083
Strand Forward strand
Band p21.3
Transcripts
ENST00000397977 ENSP00000381064
ENST00000518424 ENSP00000429011
ENST00000522114 ENSP00000430877
ENST00000520985
ENST00000521758
ENST00000523869 ENSP00000428107
ENST00000522081
ENST00000523846 ENSP00000430446
ENST00000522806
ENST00000523143
ENST00000521357 ENSP00000430704
ENST00000518799 ENSP00000429534
ENST00000519493
ENST00000520670 ENSP00000429117
ENST00000521008 ENSP00000428300
ENST00000523772 ENSP00000428608
ENST00000520827 ENSP00000428671
ENST00000517546
ENST00000607660
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031864
View Gene Order
ENSBTAG00000025003
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.512627
RefSeq NM_018142 XM_005273557
HUGO
OMIM
CCDS CCDS6011
HPRD 07686
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca