Version 5.4
Homo sapiens Gene: SFPQ
Summary
InnateDB Gene IDBG-96092.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SFPQ
Gene Name splicing factor proline/glutamine-rich
Synonyms POMP100; PPP1R140; PSF
Species Homo sapiens
Ensembl Gene ENSG00000116560
Encoded Proteins
IDBP-96096
splicing factor proline/glutamine-rich
IDBP-482744
splicing factor proline/glutamine-rich
IDBP-482248
splicing factor proline/glutamine-rich
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:35176378-35193148
Strand Reverse strand
Band p34.3
Transcripts
ENST00000357214 ENSP00000349748
ENST00000471991
ENST00000468598
ENST00000460428 ENSP00000425071
ENST00000470472 ENSP00000424440
ENST00000466745
ENST00000466213
ENST00000490668
ENST00000485365
ENST00000485454
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 166 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 166 [view]
Protein-Protein 162 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0001047 core promoter binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0042752 regulation of circadian rhythm
GO:0042754 negative regulation of circadian rhythm
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048511 rhythmic process
GO:0070932 histone H3 deacetylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
GO:0042382 paraspeckles
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028820
View Gene Order
ENSBTAG00000016328
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.355934 Hs.718162 Hs.731123
RefSeq NM_005066 XM_005271111 XM_005271112 XM_005271113 XM_005271115 XM_005271116
HUGO
OMIM
CCDS CCDS388
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca