Homo sapiens Gene: RNF11
Summary
InnateDB Gene IDBG-98444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF11
Gene Name ring finger protein 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000123091
Encoded Proteins
ring finger protein 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:51236271-51273455
Strand Forward strand
Band p32.3
Transcripts
ENST00000242719 ENSP00000242719
ENST00000494873
ENST00000486691
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 147 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 147 [view]
Protein-Protein 147 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0051865 protein autoubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005769 early endosome
GO:0055037 recycling endosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.309641 Hs.714436
RefSeq NM_014372
HUGO
OMIM
CCDS CCDS556
HPRD 09955
IMGT
EMBL
GenPept
RNA Seq Atlas