InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC6A17

Summary

InnateDB Protein

IDBP-100958.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC6A17

Protein Name

solute carrier family 6, member 17

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000330199

InnateDB Gene

IDBG-100956 (SLC6A17)

Protein Structure

UniProt Annotation

Function

Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005328	neurotransmitter:sodium symporter activity

Biological Process

GO:0006836	neurotransmitter transport
GO:0015804	neutral amino acid transport
GO:0015816	glycine transport
GO:0015820	leucine transport
GO:0015824	proline transport
GO:0032328	alanine transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0008021	synaptic vesicle
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030672	synaptic vesicle membrane