InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TSHB

Summary

InnateDB Protein

IDBP-101339.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TSHB

Protein Name

thyroid stimulating hormone, beta

Synonyms

TSH-B; TSH-BETA;

Species

Homo sapiens

Ensembl Protein

ENSP00000358530

InnateDB Gene

IDBG-101335 (TSHB)

Protein Structure

UniProt Annotation

Function

Indispensable for the control of thyroid structure and metabolism.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005179	hormone activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007267	cell-cell signaling
GO:0009653	anatomical structure morphogenesis
GO:0016486	peptide hormone processing
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

InterPro

IPR001545 Gonadotropin, beta subunit
IPR006208 Glycoprotein hormone subunit beta, cystine knot
IPR029034 Cystine-knot cytokine

PFAM

PF00007

PRINTS

PIRSF

SMART

SM00068

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P01222

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

7252

UniGene

RefSeq

HUGO

HGNC:12372

OMIM

188540

CCDS

CCDS880

HPRD

11766

IMGT

EMBL

AL109660 BC069298 M21024 M23670 M23671 M25164 S70587 X02866 X02867

GenPept

AAA36782 AAA61235 AAB05845 AAB30828 AAH69298 CAA26618 CAA26619 CAI22270