InnateDB Protein
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IDBP-10134.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DUOXA1
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Protein Name
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dual oxidase maturation factor 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000267803
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InnateDB Gene
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IDBG-10130 (DUOXA1)
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Protein Structure
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Function |
May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. {ECO:0000305PubMed:16651268}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Specifically expressed in thyroid gland. Also detected in esophagus. {ECO:0000269PubMed:16651268}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0015031
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protein transport
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GO:0042743
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hydrogen peroxide metabolic process
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GO:0045666
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positive regulation of neuron differentiation
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GO:0050727
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regulation of inflammatory response
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GO:2000379
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positive regulation of reactive oxygen species metabolic process
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GO:2000609
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regulation of thyroid hormone generation
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Cellular Component |
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PDB ID |
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InterPro |
IPR018469
Dual oxidase maturation factor
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PFAM |
PF10204
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q1HG43
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PhosphoSite |
PhosphoSite-
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TrEMBL |
H0YMZ8
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UniProt Splice Variant |
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Entrez Gene |
90527
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UniGene |
Hs.356664
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RefSeq |
NP_653166
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HUGO |
HGNC:26507
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OMIM |
612771
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CCDS |
CCDS10119
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HPRD |
14829
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IMGT |
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EMBL |
AC091117
AK056896
AK292771
BC020841
BC029819
CH471082
DQ489735
EU927396
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GenPept |
AAH20841
AAH29819
ABF48257
ACH57455
BAB71304
BAF85460
EAW77291
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