Version 5.4
Homo sapiens Protein: SPRR3
Summary
InnateDB Protein IDBP-102589.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPRR3
Protein Name small proline-rich protein 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000330391
InnateDB Gene IDBG-102587 (SPRR3)
Protein Structure
UniProt Annotation
Function Cross-linked envelope protein of keratinocytes.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0008544 epidermis development
GO:0018149 peptide cross-linking
GO:0030216 keratinocyte differentiation
GO:0031424 keratinization
GO:0042060 wound healing
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003302 Cornifin (SPRR1)
PFAM PF02389
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UBC9
PhosphoSite PhosphoSite-Q9UBC9
TrEMBL F5GZ12
UniProt Splice Variant
Entrez Gene 6707
UniGene Hs.727036
RefSeq NP_005407
HUGO HGNC:11268
OMIM 182271
CCDS CCDS1033
HPRD 01652
IMGT
EMBL AF077374 AJ243667 AK311823 AL356867 AY118269 BC017802 CH471121 DQ017955 EF553525
GenPept AAD11938 AAH17802 AAM74559 AAY26394 ABQ66270 BAG34765 CAB65098 CAI19803 EAW53353 EAW53354

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca