Version 5.4
Homo sapiens Protein: SLC50A1
Summary
InnateDB Protein IDBP-103106.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC50A1
Protein Name solute carrier family 50 (sugar transporter), member 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000357389
InnateDB Gene IDBG-103102 (SLC50A1)
Protein Structure
UniProt Annotation
Function Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1. {ECO:0000269PubMed:21107422}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:21107422}; Multi-pass membrane protein {ECO:0000269PubMed:21107422}. Cell membrane {ECO:0000269PubMed:21107422}; Multi-pass membrane protein {ECO:0000269PubMed:21107422}. Note=May also localize to the endoplasmic reticulum. {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitously expressed with highest expression in oviduct, epididymis and intestine. {ECO:0000269PubMed:21107422}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0042947 glucoside transmembrane transporter activity
Biological Process
GO:0006310 DNA recombination
GO:0008643 carbohydrate transport
GO:0042946 glucoside transport
GO:0045815 positive regulation of gene expression, epigenetic
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BRV3
PhosphoSite PhosphoSite-Q9BRV3
TrEMBL
UniProt Splice Variant
Entrez Gene 55974
UniGene Hs.292154
RefSeq NP_061333
HUGO HGNC:30657
OMIM 613683
CCDS CCDS1093
HPRD 17427
IMGT
EMBL AF126023 AF126024 AK289551 AL691442 BC005943 BC009621 CR457148
GenPept AAF17232 AAF17233 AAH05943 AAH09621 BAF82240 CAG33429 CAI15322 CAI15323 CAI15324

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca