InnateDB Protein
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IDBP-103548.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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APOA1BP
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Protein Name
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apolipoprotein A-I binding protein
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000357218
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InnateDB Gene
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IDBG-103546 (APOA1BP)
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Protein Structure
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Function |
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. {ECO:0000255HAMAP-Rule:MF_03159}.
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Subcellular Localization |
Mitochondrion {ECO:0000255HAMAP- Rule:MF_03159}. Secreted {ECO:0000255HAMAP-Rule:MF_03159, ECO:0000269PubMed:11991719}. Note=In sperm, secretion gradually increases during capacitation. {ECO:0000255HAMAP-Rule:MF_03159}.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level). {ECO:0000269PubMed:11991719}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004443
YjeF N-terminal domain
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PFAM |
PF03853
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NCW5
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PhosphoSite |
PhosphoSite-Q8NCW5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
128240
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UniGene |
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RefSeq |
NP_658985
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HUGO |
HGNC:18453
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OMIM |
608862
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CCDS |
CCDS1145
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HPRD |
16397
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IMGT |
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EMBL |
AJ315849
AK294835
AL365181
BC100931
BC100932
BC100933
BC100934
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GenPept |
AAI00932
AAI00933
AAI00934
AAI00935
BAG57944
CAC86580
CAI13051
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