InnateDB Protein
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IDBP-104180.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PFDN2
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Protein Name
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prefoldin subunit 2
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Synonyms
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PFD2;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000356989
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InnateDB Gene
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IDBG-104178 (PFDN2)
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Protein Structure
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Function |
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. {ECO:0000269PubMed:9630229}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:17936702}. Cytoplasm {ECO:0000269PubMed:17936702}. Mitochondrion {ECO:0000269PubMed:17936702}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
49
[view]
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Protein-Protein |
48
[view]
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002777
Prefoldin beta-like
IPR009053
Prefoldin
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PFAM |
PF01920
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UHV9
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PhosphoSite |
PhosphoSite-Q9UHV9
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TrEMBL |
B1AQP2
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UniProt Splice Variant |
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Entrez Gene |
5202
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UniGene |
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RefSeq |
NP_036526
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HUGO |
HGNC:8867
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OMIM |
613466
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CCDS |
CCDS1217
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HPRD |
09658
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IMGT |
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EMBL |
AF117237
AF151065
AF165883
AK315736
BC012464
BC047042
CH471121
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GenPept |
AAD47084
AAF17218
AAF36151
AAH12464
AAH47042
BAG38091
EAW52658
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