Version 5.4
Homo sapiens Protein: SUCO
Summary
InnateDB Protein IDBP-104855.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUCO
Protein Name chromosome 1 open reading frame 9
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000263688
InnateDB Gene IDBG-104851 (SUCO)
Protein Structure
UniProt Annotation
Function Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity). {ECO:0000250}.
Subcellular Localization Rough endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in pancreas and testis and to a lower extent in prostate, ovary, heart, thymus, small intestine and spleen. {ECO:0000269PubMed:10673381}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001503 ossification
GO:0007275 multicellular organismal development
GO:0032967 positive regulation of collagen biosynthetic process
GO:0045669 positive regulation of osteoblast differentiation
GO:0046850 regulation of bone remodeling
Cellular Component
GO:0005791 rough endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030867 rough endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR008979 Galactose-binding domain-like
IPR012919 Sad1/UNC-like, C-terminal
PFAM PF07738
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UBS9
PhosphoSite PhosphoSite-Q9UBS9
TrEMBL
UniProt Splice Variant
Entrez Gene 51430
UniGene Hs.743437
RefSeq NP_055098
HUGO HGNC:1240
OMIM
CCDS CCDS1303
HPRD 12732
IMGT
EMBL AF097535 AF310265 AF310266 AF310267 AF310268 AF310269 AF310270 AF310271 AF310272 AF310273 AF310274 AF310275 AF310276 AF310277 AF310278 AF310279 AF310280 AF310281 AF310282 AF310283 AF310284 AF310285 AF310286 AF310287 AF310288 AF310289 AF310290 AF310291 AF310292 AF310293 AF310294 AF310295 AF310296 AF310297 AF310298 AF310299 AF310300 AF310301 AF310302 AF310303 AF310304 AF310305 AF310306 AF310307 AF310308 AF310309 AF310310 AF310311 AF310312 AF310313 AF310314 AF310315 AF310316 AF310317 AF310318 AF310319 AF310320 AF310321 AF310322 AF310323 AF310324 AF310325 AJ250075 AL035291 BC137125 CH471067 Z94054 Z96050
GenPept AAF04619 AAI37126 AAK28742 AAK28743 AAK28744 AAK28745 AAK28746 AAK28747 AAK28748 AAK28749 AAK28750 AAK28751 AAK28752 AAK28753 AAK28754 AAK28755 AAK28756 AAK28757 AAK28758 AAK28759 AAK28760 AAK28761 AAK28762 AAK28763 AAK28764 AAK28765 AAK28766 AAK28767 AAK28768 AAK28769 AAK28770 AAK28771 AAK28772 AAK28773 AAK28774 AAK28775 AAK28776 AAK28777 AAK28778 AAK28779 AAK28780 AAK28781 AAK28782 AAK28783 AAK28784 AAK28785 AAK28786 AAK28787 AAK28788 AAK28789 AAK28790 AAK28791 AAK28792 AAK28793 AAK28794 AAK28795 AAK28796 AAK28797 AAK28798 AAK28799 AAK28800 AAK28801 AAK28802 CAA22894 CAB57360 CAI19034 CAI19460 EAW90931

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca