Version 5.4
Homo sapiens Protein: PARP1
Summary
InnateDB Protein IDBP-107042.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PARP1
Protein Name poly (ADP-ribose) polymerase 1
Synonyms ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL;
Species Homo sapiens
Ensembl Protein ENSP00000355755
InnateDB Gene IDBG-107034 (PARP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 294 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 295 [view]
Protein-Protein 292 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001510 Zinc finger, PARP-type
PFAM PF00645
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5VX85
UniProt Splice Variant
Entrez Gene 142
UniGene Hs.707776
RefSeq
HUGO HGNC:270
OMIM 173870
CCDS
HPRD 01435
IMGT
EMBL AL359704 AL359742
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca