InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ITPKB

Summary

InnateDB Protein

IDBP-107052.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ITPKB

Protein Name

inositol-trisphosphate 3-kinase B

Synonyms

IP3-3KB; IP3K; IP3K-B; IP3KB; PIG37;

Species

Homo sapiens

Ensembl Protein

ENSP00000355748

InnateDB Gene

IDBG-107048 (ITPKB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity

Biological Process

GO:0007165	signal transduction
GO:0043647	inositol phosphate metabolic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P27987

PhosphoSite

PhosphoSite-P27987

TrEMBL

UniProt Splice Variant

Entrez Gene

3707

UniGene

Hs.743604

RefSeq

XP_005273177

HUGO

HGNC:6179

OMIM

147522

CCDS

HPRD

00942

IMGT

EMBL

AJ242780 AL365444 BC015009 X57206 Y18024

GenPept

AAH15009 CAA40491 CAB65055 CAC40650 CAH70187 CAH70188