InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUP133

Summary

InnateDB Protein

IDBP-107324.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUP133

Protein Name

nucleoporin 133kDa

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000261396

InnateDB Gene

IDBG-107322 (NUP133)

Protein Structure

UniProt Annotation

Function

Involved in poly(A)+ RNA transport. {ECO:0000269PubMed:11684705}.

Subcellular Localization

Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.

Experimentally validated
Total	40 [view]
Protein-Protein	39 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005487	nucleocytoplasmic transporter activity
GO:0005515	protein binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0006406	mRNA export from nucleus
GO:0006999	nuclear pore organization
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015031	protein transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0048339	paraxial mesoderm development
GO:0055085	transmembrane transport

Cellular Component

GO:0000777	condensed chromosome kinetochore
GO:0000940	condensed chromosome outer kinetochore
GO:0005635	nuclear envelope
GO:0005643	nuclear pore
GO:0005829	cytosol
GO:0016020	membrane
GO:0031080	nuclear pore outer ring