InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CHMP7

Summary

InnateDB Protein

IDBP-11806.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHMP7

Protein Name

charged multivesicular body protein 7

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000324491

InnateDB Gene

IDBG-11804 (CHMP7)

Protein Structure

UniProt Annotation

Function

Plays a role in the endosomal sorting pathway. {ECO:0000269PubMed:16856878}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:16856878}. Note=Diffused localization, with some punctate distribution, especially in the perinuclear area.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008565	protein transporter activity

Biological Process

GO:0007034	vacuolar transport
GO:0015031	protein transport
GO:0016032	viral process
GO:0016197	endosomal transport
GO:0019058	viral life cycle
GO:0045324	late endosome to vacuole transport
GO:0061024	membrane organization

Cellular Component

GO:0000815	ESCRT III complex
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR005024 Snf7

PFAM

PF03357

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8WUX9

PhosphoSite

PhosphoSite-Q8WUX9

TrEMBL

E5RJI3

UniProt Splice Variant

Entrez Gene

91782

UniGene

Hs.5019

RefSeq

HUGO

HGNC:28439

OMIM

611130

CCDS

CCDS6040

HPRD

14534

IMGT

EMBL

AC100861 AK021776 AK092500 AK315664 AL833843 BC004344 BC019110 BC042050 CH471080

GenPept

AAH04344 AAH19110 AAH42050 BAG38030 BAG51048 BAG52561 CAD38703 EAW63632 EAW63634