Homo sapiens Protein: BRD1
Summary
InnateDB Protein IDBP-12471.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRD1
Protein Name bromodomain containing 1
Synonyms BRL; BRPF1; BRPF2;
Species Homo sapiens
Ensembl Protein ENSP00000216267
InnateDB Gene IDBG-12467 (BRD1)
Protein Structure
UniProt Annotation
Function Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. {ECO:0000269PubMed:16387653, ECO:0000269PubMed:21880731}.
Subcellular Localization Nucleus {ECO:0000269PubMed:21880731}.
Disease Associations
Tissue Specificity Highly expressed in testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0042393 histone binding
Biological Process
GO:0043966 histone H3 acetylation
Cellular Component
GO:0005634 nucleus
GO:0070776 MOZ/MORF histone acetyltransferase complex
Protein Structure and Domains
PDB ID
InterPro IPR000313 PWWP domain
IPR001487 Bromodomain
IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR019542 Enhancer of polycomb-like, N-terminal
IPR019787 Zinc finger, PHD-finger
PFAM PF00855
PF00439
PF10513
PF00628
PRINTS PR00503
PIRSF
SMART SM00293
SM00297
SM00249
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95696
PhosphoSite PhosphoSite-O95696
TrEMBL Q659H0
UniProt Splice Variant
Entrez Gene 23774
UniGene Hs.614354
RefSeq NP_055392
HUGO HGNC:1102
OMIM 604589
CCDS CCDS14080
HPRD 06848
IMGT
EMBL AF005067 AK292428 AL049402 CH471138 CR456408 Z98885
GenPept AAF34320 BAF85117 CAB11574 CAG30294 CAH56423 CAO72061 EAW73473 EAW73474 EAW73475 EAW73476