InnateDB Protein
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IDBP-12658.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RNF126
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Protein Name
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ring finger protein 126
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000292363
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InnateDB Gene
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IDBG-12656 (RNF126)
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Protein Structure
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Function |
E3 ubiquitin-protein ligase. By ubiquitinating CDKN1A/p21 and targeting it for proteasomal degradation, may promote cell proliferation. {ECO:0000269PubMed:23026136}.
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Subcellular Localization |
Cytoplasm. Nucleus.
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Disease Associations |
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Tissue Specificity |
Highly expressed in liver and testis. {ECO:0000269PubMed:23026136}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
44
[view]
|
Protein-Protein |
44
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001841
Zinc finger, RING-type
IPR018957
Zinc finger, C3HC4 RING-type
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PFAM |
PF13639
PF14634
PF00097
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PRINTS |
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PIRSF |
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SMART |
SM00184
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BV68
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PhosphoSite |
PhosphoSite-Q9BV68
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TrEMBL |
Q9NPN4
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UniProt Splice Variant |
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Entrez Gene |
55658
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UniGene |
Hs.69554
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RefSeq |
NP_919442
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HUGO |
HGNC:21151
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OMIM |
615177
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CCDS |
CCDS12039
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HPRD |
11501
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IMGT |
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EMBL |
AC004449
AK000559
AL360265
BC001442
BC025374
CH471242
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GenPept |
AAC06149
AAH01442
AAH25374
BAA91254
CAB96178
EAW61168
EAW61173
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