Version 5.4
Mus musculus Protein: Mios
Summary
InnateDB Protein IDBP-128383.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mios
Protein Name missing oocyte, meiosis regulator, homolog (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039301
InnateDB Gene IDBG-128381 (Mios)
Protein Structure
UniProt Annotation
Function As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005765 lysosomal membrane
Protein Structure and Domains
PDB ID MGI:2182066
InterPro IPR001680 WD40 repeat
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VE19
PhosphoSite PhosphoSite-Q8VE19
TrEMBL Q8BV62
UniProt Splice Variant
Entrez Gene 252875
UniGene Mm.414967
RefSeq NP_663349
MGI ID
MGI Symbol Mios
OMIM
CCDS CCDS39425
HPRD
IMGT
EMBL AC158661 AK079844 BC020002
GenPept AAH20002 BAC37763

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca