Version 5.4
Mus musculus Protein: Eif1ad
Summary
InnateDB Protein IDBP-131375.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif1ad
Protein Name eukaryotic translation initiation factor 1A domain containing
Synonyms 2010003J03Rik; AI131644;
Species Mus musculus
Ensembl Protein ENSMUSP00000025759
InnateDB Gene IDBG-131373 (Eif1ad)
Protein Structure
UniProt Annotation
Function Plays a role into cellular response to oxidative stress. Decreases cell proliferation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005634 nucleus
GO:0043231 intracellular membrane-bounded organelle
GO:0045111 intermediate filament cytoskeleton
Protein Structure and Domains
PDB ID MGI:1917110
InterPro IPR001253 Translation initiation factor 1A (eIF-1A)
IPR006196 RNA-binding domain, S1, IF1 type
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF01176
PRINTS
PIRSF
SMART SM00652
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3THJ3
PhosphoSite PhosphoSite-Q3THJ3
TrEMBL
UniProt Splice Variant
Entrez Gene 69860
UniGene
RefSeq NP_081512
MGI ID
MGI Symbol Eif1ad
OMIM
CCDS CCDS29459
HPRD
IMGT
EMBL AK008070 AK153194 AK158977 AK168102 AK168253 AK168598 BC024640
GenPept AAH24640 BAB25440 BAE31794 BAE34752 BAE40073 BAE40203 BAE40465

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca