Version 5.4
Mus musculus Protein: Fbxo30
Summary
InnateDB Protein IDBP-133603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo30
Protein Name F-box protein 30
Synonyms 1700026A16Rik; MUSA1;
Species Mus musculus
Ensembl Protein ENSMUSP00000068230
InnateDB Gene IDBG-133601 (Fbxo30)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation. {ECO:0000269PubMed:24076600}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1919115
InterPro IPR001293 Zinc finger, TRAF-type
IPR001810 F-box domain
IPR008974 TRAF-like
PFAM PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BJL1
PhosphoSite PhosphoSite-Q8BJL1
TrEMBL
UniProt Splice Variant
Entrez Gene 71865
UniGene Mm.403301
RefSeq NP_001161769
MGI ID
MGI Symbol Fbxo30
OMIM
CCDS CCDS23697
HPRD
IMGT
EMBL AK006369 AK083479 AK135274 BC037691 CH466562
GenPept AAH37691 BAB24551 BAC38931 BAE22469 EDL03517

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca